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mouse anti human hnf1 α antibody  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology mouse anti human hnf1 α antibody
    Sequences of primers used for real-time quantitative polymerase chain reaction.
    Mouse Anti Human Hnf1 α Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 189 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti+human+hnf1+%CE%B1+antibody/HNF-1%CE%B1+Antibody/pmc06659460-59-62-72
    Average 93 stars, based on 189 article reviews
    mouse anti human hnf1 α antibody - by Bioz Stars, 2026-08
    93/100 stars

    Images

    1) Product Images from "Inflammation Induces Lipid Deposition in Kidneys by Downregulating Renal PCSK9 in Mice with Adriamycin-Induced Nephropathy"

    Article Title: Inflammation Induces Lipid Deposition in Kidneys by Downregulating Renal PCSK9 in Mice with Adriamycin-Induced Nephropathy

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    doi: 10.12659/MSM.917312


    Figure Legend Snippet: Sequences of primers used for real-time quantitative polymerase chain reaction.

    Techniques Used: Sequencing

    ( A–F ) Renal expression of TGF-β1, IL-1β, HNF1α, PCSK9, LDLR, and SREBP2 proteins (immunohistochemical analysis software was used to analyze the optical density values in the images, and semi-quantitative values of positive expression in kidney tissues were obtained) and mRNAs (from RT-qPCR, relative to GAPDH) in the 4 groups at 4, 8, and 12 weeks. Values represent means ± standard errors of mean for groups of 8 mice each. For comparisons at the same time point: * P <0.05 versus CTL, # P <0.05 versus AWI. TGF-β1 – transforming growth factor beta 1; IL-1β – interleukin 1β; HNF1α – hepatocyte nuclear factor 1α; PCSK9 – pro-protein convertase subtilisin kexin type 9; LDLR – low-density lipoprotein receptor; SREBP2 – sterol regulatory element binding protein 2; RT-q-PCR – real-time quantitative polymerase chain reaction; GAPDH – glyceraldehyde 3-phosphate dehydrogenase; CLT – control group; AWI group – Adriamycin-induced nephrosis with inflammation group.
    Figure Legend Snippet: ( A–F ) Renal expression of TGF-β1, IL-1β, HNF1α, PCSK9, LDLR, and SREBP2 proteins (immunohistochemical analysis software was used to analyze the optical density values in the images, and semi-quantitative values of positive expression in kidney tissues were obtained) and mRNAs (from RT-qPCR, relative to GAPDH) in the 4 groups at 4, 8, and 12 weeks. Values represent means ± standard errors of mean for groups of 8 mice each. For comparisons at the same time point: * P <0.05 versus CTL, # P <0.05 versus AWI. TGF-β1 – transforming growth factor beta 1; IL-1β – interleukin 1β; HNF1α – hepatocyte nuclear factor 1α; PCSK9 – pro-protein convertase subtilisin kexin type 9; LDLR – low-density lipoprotein receptor; SREBP2 – sterol regulatory element binding protein 2; RT-q-PCR – real-time quantitative polymerase chain reaction; GAPDH – glyceraldehyde 3-phosphate dehydrogenase; CLT – control group; AWI group – Adriamycin-induced nephrosis with inflammation group.

    Techniques Used: Expressing, Immunohistochemical staining, Software, Quantitative RT-PCR, Binding Assay, Real-time Polymerase Chain Reaction, Control

    Representative immunostaining results of renal tissues for HNF1α, PCSK9, LDLR, and SREBP2 in each group at 4, 8, and 12 weeks. Scale bars indicate 100 μm. HNF1α – hepatocyte nuclear factor 1α; PCSK9 – pro-protein convertase subtilisin kexin type 9; LDLR – low-density lipoprotein receptor; SREBP2 – sterol regulatory element binding protein 2.
    Figure Legend Snippet: Representative immunostaining results of renal tissues for HNF1α, PCSK9, LDLR, and SREBP2 in each group at 4, 8, and 12 weeks. Scale bars indicate 100 μm. HNF1α – hepatocyte nuclear factor 1α; PCSK9 – pro-protein convertase subtilisin kexin type 9; LDLR – low-density lipoprotein receptor; SREBP2 – sterol regulatory element binding protein 2.

    Techniques Used: Immunostaining, Binding Assay



    Similar Products

    mouse anti human hnf1 α antibody  (Santa Cruz Biotechnology)
    93
    Santa Cruz Biotechnology mouse anti human hnf1 α antibody
    Sequences of primers used for real-time quantitative polymerase chain reaction.
    Mouse Anti Human Hnf1 α Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti+human+hnf1+%CE%B1+antibody/HNF-1%CE%B1+Antibody/pmc06659460-59-62-72
    Average 93 stars, based on 1 article reviews
    mouse anti human hnf1 α antibody - by Bioz Stars, 2026-08
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Inflammation Induces Lipid Deposition in Kidneys by Downregulating Renal PCSK9 in Mice with Adriamycin-Induced Nephropathy

    doi: 10.12659/MSM.917312

    Figure Lengend Snippet: Sequences of primers used for real-time quantitative polymerase chain reaction.

    Article Snippet: Immunohistochemistry (IHC) was used to examine the expression of interleukin (IL)-1β, transforming growth factor beta 1 (TGF-β1), HNF1α, PCSK9, LDLR, and SREBP2 using the following antibodies: rabbit anti-rat IL-1β antibody (working dilution 1: 100; sc-7884, Santa Cruz Biotechnology, USA), rabbit anti-rat TGF-β1 (working dilution 1: 100; sc-146, Santa Cruz Biotechnology), mouse anti-human SREBP2 antibody (working dilution 1: 100; sc-271615, Santa Cruz Biotechnology), mouse anti-human HNF1 α antibody (working dilution 1: 100; sc-393668, Santa Cruz Biotechnology,), rabbit anti-rat LDLR antibody (working dilution 1: 100; ab30532, Abcam, UK), rabbit anti-rat PCSK9 antibody (working dilution 1: 100; ab31762, Abcam).

    Techniques: Sequencing

    ( A–F ) Renal expression of TGF-β1, IL-1β, HNF1α, PCSK9, LDLR, and SREBP2 proteins (immunohistochemical analysis software was used to analyze the optical density values in the images, and semi-quantitative values of positive expression in kidney tissues were obtained) and mRNAs (from RT-qPCR, relative to GAPDH) in the 4 groups at 4, 8, and 12 weeks. Values represent means ± standard errors of mean for groups of 8 mice each. For comparisons at the same time point: * P <0.05 versus CTL, # P <0.05 versus AWI. TGF-β1 – transforming growth factor beta 1; IL-1β – interleukin 1β; HNF1α – hepatocyte nuclear factor 1α; PCSK9 – pro-protein convertase subtilisin kexin type 9; LDLR – low-density lipoprotein receptor; SREBP2 – sterol regulatory element binding protein 2; RT-q-PCR – real-time quantitative polymerase chain reaction; GAPDH – glyceraldehyde 3-phosphate dehydrogenase; CLT – control group; AWI group – Adriamycin-induced nephrosis with inflammation group.

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Inflammation Induces Lipid Deposition in Kidneys by Downregulating Renal PCSK9 in Mice with Adriamycin-Induced Nephropathy

    doi: 10.12659/MSM.917312

    Figure Lengend Snippet: ( A–F ) Renal expression of TGF-β1, IL-1β, HNF1α, PCSK9, LDLR, and SREBP2 proteins (immunohistochemical analysis software was used to analyze the optical density values in the images, and semi-quantitative values of positive expression in kidney tissues were obtained) and mRNAs (from RT-qPCR, relative to GAPDH) in the 4 groups at 4, 8, and 12 weeks. Values represent means ± standard errors of mean for groups of 8 mice each. For comparisons at the same time point: * P <0.05 versus CTL, # P <0.05 versus AWI. TGF-β1 – transforming growth factor beta 1; IL-1β – interleukin 1β; HNF1α – hepatocyte nuclear factor 1α; PCSK9 – pro-protein convertase subtilisin kexin type 9; LDLR – low-density lipoprotein receptor; SREBP2 – sterol regulatory element binding protein 2; RT-q-PCR – real-time quantitative polymerase chain reaction; GAPDH – glyceraldehyde 3-phosphate dehydrogenase; CLT – control group; AWI group – Adriamycin-induced nephrosis with inflammation group.

    Article Snippet: Immunohistochemistry (IHC) was used to examine the expression of interleukin (IL)-1β, transforming growth factor beta 1 (TGF-β1), HNF1α, PCSK9, LDLR, and SREBP2 using the following antibodies: rabbit anti-rat IL-1β antibody (working dilution 1: 100; sc-7884, Santa Cruz Biotechnology, USA), rabbit anti-rat TGF-β1 (working dilution 1: 100; sc-146, Santa Cruz Biotechnology), mouse anti-human SREBP2 antibody (working dilution 1: 100; sc-271615, Santa Cruz Biotechnology), mouse anti-human HNF1 α antibody (working dilution 1: 100; sc-393668, Santa Cruz Biotechnology,), rabbit anti-rat LDLR antibody (working dilution 1: 100; ab30532, Abcam, UK), rabbit anti-rat PCSK9 antibody (working dilution 1: 100; ab31762, Abcam).

    Techniques: Expressing, Immunohistochemical staining, Software, Quantitative RT-PCR, Binding Assay, Real-time Polymerase Chain Reaction, Control

    Representative immunostaining results of renal tissues for HNF1α, PCSK9, LDLR, and SREBP2 in each group at 4, 8, and 12 weeks. Scale bars indicate 100 μm. HNF1α – hepatocyte nuclear factor 1α; PCSK9 – pro-protein convertase subtilisin kexin type 9; LDLR – low-density lipoprotein receptor; SREBP2 – sterol regulatory element binding protein 2.

    Journal: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

    Article Title: Inflammation Induces Lipid Deposition in Kidneys by Downregulating Renal PCSK9 in Mice with Adriamycin-Induced Nephropathy

    doi: 10.12659/MSM.917312

    Figure Lengend Snippet: Representative immunostaining results of renal tissues for HNF1α, PCSK9, LDLR, and SREBP2 in each group at 4, 8, and 12 weeks. Scale bars indicate 100 μm. HNF1α – hepatocyte nuclear factor 1α; PCSK9 – pro-protein convertase subtilisin kexin type 9; LDLR – low-density lipoprotein receptor; SREBP2 – sterol regulatory element binding protein 2.

    Article Snippet: Immunohistochemistry (IHC) was used to examine the expression of interleukin (IL)-1β, transforming growth factor beta 1 (TGF-β1), HNF1α, PCSK9, LDLR, and SREBP2 using the following antibodies: rabbit anti-rat IL-1β antibody (working dilution 1: 100; sc-7884, Santa Cruz Biotechnology, USA), rabbit anti-rat TGF-β1 (working dilution 1: 100; sc-146, Santa Cruz Biotechnology), mouse anti-human SREBP2 antibody (working dilution 1: 100; sc-271615, Santa Cruz Biotechnology), mouse anti-human HNF1 α antibody (working dilution 1: 100; sc-393668, Santa Cruz Biotechnology,), rabbit anti-rat LDLR antibody (working dilution 1: 100; ab30532, Abcam, UK), rabbit anti-rat PCSK9 antibody (working dilution 1: 100; ab31762, Abcam).

    Techniques: Immunostaining, Binding Assay